Central Diabetes Insipidus Causes

Nephrogenic diabetes insipidus ndi is a rare kidney disorder that may be inherited or acquired. In about half the cases doctors don t know what causes central diabetes insipidus.

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Ndi is caused by complete or partial resistance of the kidneys to arginine vasopressin avp.

Central diabetes insipidus causes. It may be due to damage to the brain caused by. Other times it happens because of damage or injury to the hypothalamus or pituitary gland. Some causes result from an abnormality in the gene responsible for vasopressin secretion.

The cause of primary central diabetes insipidus is often unknown. Cdi is classified into three subtypes. Reduction of fluid has little effect on the concentration of the urine.

Confusion and changes in alertness due to dehydration and higher than normal sodium level in the body if the person is unable to drink. The amount of urine produced can be nearly 20 liters per day. Central diabetes insipidus is a lack of the hormone vasopressin antidiuretic hormone that causes excessive production of very dilute urine polyuria.

Nephrogenic diabetes insipidus occurs when there s a defect in the kidney. Dehydration confusion loss of consciousness. Damage to the pituitary gland or hypothalamus from surgery a tumor a head injury or an.

The secondary type is acquired through. Central diabetes insipidus has several causes including a brain tumor a brain injury brain surgery tuberculosis and some forms of other diseases. Idiopathic secondary and familial.

Benign suprasellar tumors 20 of cases infections encephalitis tuberculosis etc trauma 17 of cases or neurosurgery 9 of cases non infectious granuloma sarcoidosis langerhans cell histiocytosis etc leukaemia autoimmune associated with. The cause varies depending on the type of diabetes insipidus you have. Complications may include dehydration or seizures.

Central diabetes insipidus cdi characterized by polyuria and polydipsia is caused by deficiency of arginine vasopressin avp an antidiuretic hormone which acts on v2 receptors in kidney to promote reabsorption of free water. Diabetes insipidus di is a condition characterized by large amounts of dilute urine and increased thirst. Symptoms of central diabetes insipidus include.

In severe cases or if a person can t get enough liquid to drink central diabetes insipidus can cause. There are four types of di each with a different set of causes.

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